Synthesis of oligonucleotides possessing versatile probes for PET labelling and their rapid ligand-free click reaction.

نویسندگان

  • Takao Shiraishi
  • Yoshiaki Kitamura
  • Yoshihito Ueno
  • Yukio Kitade
چکیده

We synthesised aryl acetylene derivatives as versatile probes for labelling of oligonucleotides. RNA oligomers bearing an aryl acetylene molecule rapidly reacted with benzylazide derivatives under ligand-free click reaction conditions.

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عنوان ژورنال:
  • Chemical communications

دوره 47 9  شماره 

صفحات  -

تاریخ انتشار 2011